Agreement Of Retinal Nerve Fiber Layer

For the 45 eyes included in the data analysis, the average image quality for RNFL scans was 30.6 ± 4.93 and 9.0 ± 0.82 for Spectralis and Cirrus scans. The average measure of total RNFL thickness was 97.9 ± 7.9 m for spectralis and 91.2 ± 8.4 m for Cirrus. The agreement on RNFL measures using both instruments was assessed using bland-Altman-Plots, intraclass coefficient correlation (CCI) and tage tests. The Bland-Altman plots offer a graphic method for comparing the two methods. The average difference and 95% of compliance limits can be used to determine whether the difference between two methods is clinically acceptable.60 The intraklassifkative correlation coefficient (CCI) is a measure of reliability calculated by comparing differences between subjects and overall variance. In general, concordance is considered good when one-third of the difference between subjects (ICC ≥ 0.75) in the subject deviation is a good match between the measurements.61 T-couples tests were also used to test the hypothesis that the difference in RNFL thickness measurements with both instruments is zero. Table 3. Interval of differences between calculated values and actual values of the average layer of peripapliferal nerve fibers for Spectralis and Stratus OCT. An assessment of the retinal nerve fiber layer (RNFL) provides important information about the health of the optic nerve.

There are several non-invasive technologies, including optical coherence computed tomography (SD-OCT) for spectral domains that can be used for in vivo imaging and RNFL quantification, but there are often discrepancies in the thickness of RNFL between clinical instruments. The objective of this study was to study the influence of scancentation, eye enlargement and segmentation on the degree of compliance of RNFL thickness measurements by two SD-OCT instruments. The objective of this study was to assess the reproducibility of RNFL thicknesses obtained with Stratus and Spectralis. We analyzed the correlation and correspondence between the two devices between normal individuals to determine whether the RNFL measurements obtained with these devices can be used interchangeably in clinical evaluations. The pRNFLT color code agreement (green, yellow, red and white), as previously described by Rebolleda et al14, was analyzed by the Cohen code for average data after the use of the 4 methods mentioned above. The average pRNFLT measurements of all participants included in this study were used to obtain age-corrected values for the first percentile, fifth percentile and 95th percentile. The shift from TD-OCT to SD-OCT imaging to pRNFLT documentation and monitoring the structural evolution of glaucoma raises questions about the agreement and predictability of pRNFLT between the two different OCT technologies. In this study, we showed that pRNFLT, obtained by spectralis OCT and Stratus OCT, has a high match and good predictability for average pRNFLT measurements. Optical Coherence Tomography (OCT), first introduced in 1991 by Huang et al1, is a non-contact invasive imaging technology that uses subliminal interferometry to create cross-sectional images of the retinal nerve fiber layer (RNFL), macula and optical head.2, 3, 4, 5, 6, 7 There are currently two categories of OCT technology.

: the temporal domain (TD) oct and the spectral domain (SD).

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